Glioblastoma multiforme (GBM) is the most malignant brain tumor with an extremely poor prognosis.The Cancer Genome Atlas (TCGA) database has been used to confirm the roles played by 10 canonical oncogenic signaling pathways in various cancers.The purpose of this study was to evaluate the expression of genes in these 10 canonical oncogenic signaling
The strut chordae (SC) have a unique structure and play an important role in reinforcing the tunnel-shaped configuration of the mitral valve (MV) Nylon straps at the inflow and outflow tracts.We investigated the effect of varying the SC insertion location on normal MV function and dynamics to better understand the complex MV structures.A virtual pa
This paper analyzes the extent to which economic policy uncertainty affects presidential approval in four Latin American countries (Brazil, Chile, Colombia, and Mexico).Using panel (time-series cross-sectional) estimation methods, we show that economic non-shipped-product policy uncertainty has a negative impact on presidential approval in our samp
Chronic pruritus is a major symptom of atopic dermatitis (AD).Its etiopathogenesis is complex, and an understanding of the driving factors of its pathogenesis allows for the development of new molecule-targeted therapies.Dupilumab, targeting and blocking interleukin-4 (IL-4) and interleukin-13 (IL-13) molecules, has shown great efficacy in treating